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Glucomannan should be taken with enough water because it can swell and create a choking risk if used incorrectly

Based on current clinical evidence, tirzepatide is the most effective pharmacological weight loss therapy for adults without type 2 diabetes

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Next-generation therapies : Ongoing trials are exploring triple-action drugs targeting GLP-1, GIP, and glucagon receptors, potentially amplifying weight-loss effects

Nrf2 also regulates the expression of proteins participating in phase II detoxification processes carried out by glutathione-S-transferase and involves the association of glutathione (GSH) with xenobiotics and/or toxic materials (97)